SOME ACRIDINE-RESISTANT MUTATIONS OF BACTERIOPHAGE T4D
نویسندگان
چکیده
منابع مشابه
Acridine-resistant mutants of T2H bacteriophage.
mechanisms which prevent formation of infective T2H bacteriophage in T ~ c h r i c h i a coli in the presence of acridine dyes are unknown. That interruption of normal maturation occurs in a late stage of phage development was suggested by the work of FOSTER (1948) and has been substantiated physiologically and cytologically. DEMARS, LURIA, FISHER and LEVINTHAL ( 1953) and DEMARS (1955) found i...
متن کاملA map of molecular distances between mutations of bacteriophage T4D.
map of physical distances along the complete T4 DNA molecule has been A reported by MOSIG (1 968). This map was obtained using T4 phage particles, which contain considerably less DNA than a complete genome (petit particles). Each of these particles contains a continuous and probably random permutation of the T4 DNA molecule. MOSIG estimated the ratio of petit particles which carried a particula...
متن کاملPolynucleotide ligase in bacteriophage T4D recombination.
Following infection of E. coli B with ligase-deficient rII bacteriophage T4D recombination between linked markers is increased 4.2 fold and heterozygote frequency increased 2.3 fold. In such infection recombination occurs at a rapid rate for an extended period. This is in contrast to the time course of recombination observed in wild-type, lysis-inhibited, or lysis-defective (gene t defective) i...
متن کاملA Comparative Genetic Study of Conditional Lethal Mutations of Bacteriophage T4d.
WO types of conditional lethal mutations have been described for bacteriophage T4D. Amber (am) mutants can propagate in Escherichia coli K-12 (strain CR63) but are unable to complete a successful infective cycle of growth in strain B (EPSTEIN, STEINBERG and BOLLE 1964). Temperature-sensitive ( t s ) mutants can grow in either strain at 25"C, but unlike the wild-type phage from which they are de...
متن کاملEffects of deletion mutations on high negative interference in T4D bacteriophage.
IGH Negative interference (HNI) was initially described in T4 bacteriophage by CHASE and DOERMANN (1958). It is the phenomenon in which the frequency of douhle recomb;nants in crosces of the type rurc by T b is much greater than the value predicted from the frequencies of recombination in the intervals r,rb and rbre and the assumption that double recombinants arise from independent events. We w...
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ژورنال
عنوان ژورنال: Genetics
سال: 1974
ISSN: 1943-2631
DOI: 10.1093/genetics/78.2.579